Dinosaur Jr “No Bones” at SXSW Music 2009
The Future Of Clean Thermal Technologies: Technology Developments, Key Costs And The Future Outlook-Aarkstore Enterprise
This report explains the basics of drug lifecycle and investigates three goals in optimizing product potential- expanding the drug’s patent protected lifespan, accessing broader patient populations and launching line-extensions via FDCs.
The key success factors in each of these pursuits have been clearly identified, emerging trends have been presented and the underlying concepts have been explained to give the reader a clear understanding of current industry dynamics. Case studies on popular products have been used to illustrate these concepts in the real world.
An in-depth analysis of drug approval data provides context for the issues discussed. This information is juxtaposed with historic sales data to explore the correlation between the strategies employed and revenue potential.
Drug manufacturers must make the best strategic use of the patent-protected lifespan of a drug, or else risk losing the profit incentives they perceived at the start of the project.
In light of the increasing complexity of biopharmaceutical patenting, the ‘freedom to operate’, i.e. to commercialize the invention, is coming under increasing scrutiny.
The US Congress’ emerging stance on data exclusivity provisions for biologics will define the length of time a biotechnology company can keep out generic competition in new indications. The biotech industry’s stance is that the current provisions do not provide for enough time to profit from their post-approval R&D investments.
The potential for post-approval label expansion is much greater for biologics in comparison to small molecule pharmaceutical drugs. Most biologics on the market today can expect to add significant revenue streams via new indications, and potentially extend their commercial lifespan.
Over 45% of all new indication approvals granted by the FDA since 1998 belong to drugs that fall in the Genito-urinary system and Nervous system.
If an FDC is launched close to the loss of exclusivity date of the constituent brand, it may be interpreted as a marketing tactic to limit post-LoE revenue losses. If launched early, it may show intent to cater to a genuine unmet need, or to legitimately maximize the potential of the parent molecule(s).
In-depth case studies explore the real-world execution of the issues and challenges discussed in the report.
Analysis of historic drug approval data provides the reader with contextual reference points.
Case studies on Vytorin, Advair and BiDil illustrate the strategies employed by three leading FDC brands.
Brand histories of Yaz, Remicade and Seroquel show how label expansion is fundamental to successful lifecycle management.
Where applicable, these strategies are discussed with reference to specific therapeutic areas or geographies.
Issues related to biologics are highlighted to indicate where they differ from small molecule drugs.
Gain an understanding of legal provision for patent protection and data exclusivity. Understand their role in the context of product lifecycle management
Utilize the historical data on NDA approvals to identify trends and build assumptions into competitive landscape forecasts.
Understand the stance of key stakeholders and implications of off-label drug usage.
Understand the role of FDCs in optimizing the commercial potential of a product asset, and the main challenges in their commercialization
Juxtapose historic sales performance with the timing of indication expansion and FDC based strategies to assess the success or failure
Gadget Show Web TV – Kodak Easyshare Printer
What Technology Has Shaped Your Life?
Using Technology to Create a Year-round Event
Intel Rockstar TV Commercial – Sponsors of Tomorrow (High Quality)
Search Engine Optimisation: How you can make your site more searchable
Experience in providing Search Engine Optimisation (SEO) and Internet marketing solutions is something extremely useful to have in the modern world. Today, it is absolutely essential to pair together the business and the Internet. There is a simple goal here: to make the Internet an accessible and successful addition to all businesses.
So, this will mean making your website attractive and visible to browsers by using natural Internet Search Engine Optimisation (SEO) and Paid Advertising methods such as Pay Per Click. Things such as Internet marketing and Search engine optimisation will help drive more unique visitors to your website. Web marketing is much more complex than simple submissions to search engines; to achieve increased volumes of traffic, a website needs to be engineered for searching.
One way of promoting your business on the Internet is through successful Organic Marketing. Every business can achieve 1st Page Search Engine Optimisation Listings and make it onto the first page, if not the top, of all major search engines.Due to extensive research, it’s necessary to know what works and what doesn’t in SEO. The basis of this is pure optimisation of the code in your site. All Search Engine Optimisation (SEO) techniques should be natural and ethical: under no circumstances should spam or unauthorised techniques be used.And, it needs to be understood that changes will always be a feature in the world of search engine.
A lot of research is essential to develop your knowledge of SEO, and constant monitoring of what gets results and what does not will help increase the amount of traffic to your website.SEO – An Explanation of Search Engine OptimisationSearch Engine Optimisation (SEO) is the practice of modifying a website so that it is Search Engine Friendly. If a website can be properly read by the search engine spiders, there is an increased probability of achieving desirable results in the Search Engine Result Pages (SERPs). A lot of understanding is needed as to what the search engines are looking for and which techniques they give greater credibility to. “Black Hat” techniques should be avoided at all costs: they are only used to deceive the search engines. Only natural and ethical Internet marketing techniques should be used that are approved by the Search Engines. That is how search engine listing results are produced with longevity. Search Engines, such as Google or Yahoo! send computer programs known as “spiders” or “robots” to scan your website. The task in hand is to understand how to present these spiders with the information they are looking for so that the search engines can determine the value of your web site. KeywordsSearch engine optimisation success is largely dependent upon the keywords required. You should contact a company to talk about this. Information about this cannot be published because it is commercially sensitive.
How can you make your site more searchable? It’s simple really: intelligent keyword choices, well written source code, and relevant content presented clearly to both the user and search engine alike. This will achieve good, long term results. Search Engines change their rules all the timeEvery year the search engines make major changes for both commercial and quality reasons. Google, Yahoo! and Bing regularly “spring clean” their listings. This is to ensure that only relevant sites are listed, and to remove sites that are using trick optimisation methods. The search engines regularly acquire new search technology companies and launch new spiders and paid inclusion methods.The search engines spider a massive number of files. There are 8 Billion plus web pages held in Google’s database. Work and devotion to SEO will make sure that your website isn’t just a drop in the ocean.
